Minna Kellomäki (Tampere University, TAU), Katriina Aalto-Setälä (TAU), Jari Hyttinen (TAU), Pasi Kallio (TAU), Susanna Miettinen (TAU) and Susanna Narkilahti (TAU)
The Centre of Excellence in Body-on Chip Research is based on strong, existing collaboration between the participating research groups and on joint research results produced in the Human Spare Parts project. The CoE combines know-how in biological and engineering sciences to develop a new “body-on-chip” platform.
The platform will consist of several cultured tissue blocks connected with cultured vasculature and nervous systems. The way it works is that the computer-integrated nervous system stimulates, analyses and even controls different biological processes in vitro. To achieve this goal, the researchers will combine multidisciplinary expertise on human stem cells, biomaterials, sensors, microfluidics, biomodelling and bioimaging.
The CoE will produce comprehensive knowledge, for example, on understanding tissue interactions, constructing complex in vitro tissue co-cultures and controlling their functionalities. The resulting expertise and technologies will improve, for instance, the development of new personalised treatments and drugs.