Biological Barrier Mechanics and Disease: From molecular-scale to tissue-level understanding of signal integration and forces
Ivaska Johanna (University of Turku, UT); Lappalainen Pekka (University of Helsinki, UH); Saharinen Pipsa (UH); Vattulainen Ilpo (UH) and Wickström Sara (UH)
From time to time, all people suffer from some sort of infection or inflammation induced by the same cause: the impaired function of biological barriers that protect the body and organ functions. In severe cases, failure of these barriers can lead to cancer or organ failure. Understanding how biological barriers function is without a doubt one of the cornerstones of health, but nonetheless our understanding of these mechanisms is still in its infancy.
The goal of the Centre of Excellence in Biological Barrier Mechanics and Disease is to uncover how biological barriers are controlled at the level of molecules, cells and tissues. Based on this knowledge, the research will also elucidate how malfunctions of biological barriers lead to diseases, and how these diseases could be treated.