The Centre of Excellence in Complex Disease Genetics aimed to produce novel understanding of the genetic and lifestyle risk factors predisposing to common human diseases. The main focus of the CoE's research was on disorders of the central nervous and cardiovascular systems and their trait components.
During the 2006–2011 term, researchers at the CoE worked to explore the genetic background of these diseases and to increase our understanding of the relationship between genetic as well as lifestyle and environmental risks. Using the results of its studies, the CoE expected to build databases and develop novel biocomputational and biostatistical strategies. The Unit was also an Academy of Finland Centre of Excellence in Research in 2000–2005.
The CoE was headed by Professor Jaakko Kaprio.