Neoplasms, commonly known as tumours, are a challenging disease group as every single case is unique. Environmental factors, genomes, epigenetic modifications and combinations of these all play a significant role in the disease process. Researchers in the Centre of Excellence in Tumour Genetics Research have previously made important discoveries in identifying major human tumour genes, thus increasing understanding of the basic concepts of neoplastic growth. This creates a solid foundation for the CoE’s research.
Technological advances have facilitated the genome-wide characterisation of individuals and cancers. Research has produced an enormous amount of new data, and the rapid advances in technologies continue to open up opportunities towards novel scientific breakthroughs.
The CoE can advance beyond the state-of-the-art in improving the understanding of genome function by using large datasets and by creating and analysing new datasets from patient populations identified via unique Finnish registries. The CoE will bring genomic medicine into practice; a timely goal as reflected by the Finnish Government’s decision to establish the National Genome and Cancer Centres.