Elina Ikonen

1.1.2010 - 31.12.2014
University of Helsinki
cell and developmental biology

The research interests of Professor Elina Ikonen of the University of Helsinki focus on cholesterol and particularly on cholesterol transport mechanisms. She has access to new and unique techniques with which to analyse the transfer of cholesterol and related lipids in living cells and tissue. Her studies will pave the way to a better understanding of the normal function of cholesterol and its adverse effects at the cell and tissue level.

Professor Ikonen’s projects are aimed at exploring the mechanisms of cholesterol transport, which are central to cholesterol-related disease conditions in humans. The purpose of cell studies is to identify new proteins that are important for the movement of cholesterol within and out of cells. At the tissue level, specific research interests include the role of cholesterol and related lipids in the brain both in the normal development of brain tissue and in brain diseases. The information from these studies will help to improve the diagnosis and monitoring of cholesterol-related diseases, including cardiovascular and several brain diseases, and to help prescribe cholesterol medication to the people who benefit the most.

Professor Ikonen’s imaging methods open up new opportunities to explore cholesterol metabolism. Her work offers real potential for major scientific breakthroughs. It is expected that Ikonen’s studies will help towards a better understanding of cholesterol-related diseases, which with population ageing are a growing public health and economic concern.